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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DLAT
All Species:
30.3
Human Site:
T309
Identified Species:
41.67
UniProt:
P10515
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10515
NP_001922.2
647
68997
T309
A
F
A
D
Y
R
P
T
E
V
T
D
L
K
P
Chimpanzee
Pan troglodytes
XP_522180
647
68973
T309
A
F
A
D
Y
R
P
T
E
V
T
D
L
K
P
Rhesus Macaque
Macaca mulatta
XP_001107013
647
68918
T309
A
F
A
D
Y
R
P
T
E
V
T
D
L
K
P
Dog
Lupus familis
XP_546524
647
68802
T309
A
F
A
D
Y
R
P
T
E
V
T
D
L
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMF4
642
67923
T308
A
F
A
D
Y
R
P
T
E
V
T
S
L
K
P
Rat
Rattus norvegicus
P08461
632
67147
T299
A
F
A
D
Y
R
P
T
E
V
T
S
L
K
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509202
536
56600
A215
S
P
S
T
P
A
S
A
A
A
F
A
A
S
P
Chicken
Gallus gallus
XP_417933
681
72018
T338
A
F
A
D
Y
Q
E
T
A
V
T
D
M
K
A
Frog
Xenopus laevis
NP_001082239
628
66845
S286
S
F
A
D
Y
K
E
S
T
G
V
V
D
I
K
Zebra Danio
Brachydanio rerio
NP_997832
652
69250
T309
A
F
A
D
Y
V
E
T
G
V
A
A
S
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609118
512
54233
A193
P
A
P
A
A
A
A
A
P
P
P
P
P
P
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19749
507
53448
P188
K
A
P
E
P
A
K
P
A
A
S
S
Q
P
S
Sea Urchin
Strong. purpuratus
XP_001190217
487
52117
P168
Q
V
A
A
P
P
P
P
P
P
R
P
P
P
P
Poplar Tree
Populus trichocarpa
XP_002303212
512
55370
H193
A
P
T
P
P
A
S
H
K
E
E
V
E
K
P
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q5M729
539
58449
K220
E
P
T
P
A
P
P
K
E
E
K
V
K
Q
P
Baker's Yeast
Sacchar. cerevisiae
P12695
482
51800
K163
K
T
S
A
P
E
A
K
K
S
D
V
A
A
P
Red Bread Mold
Neurospora crassa
P20285
458
48601
E139
S
P
A
V
P
K
D
E
P
K
N
E
S
T
A
Conservation
Percent
Protein Identity:
100
99.2
98.1
89.4
N.A.
85.6
85.1
N.A.
70.3
72
72.8
71.9
N.A.
42
N.A.
41.7
39.8
Protein Similarity:
100
99.2
98.6
92.8
N.A.
90.2
89.6
N.A.
74.5
78.4
82.6
78.9
N.A.
53.9
N.A.
55
54.1
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
6.6
66.6
26.6
53.3
N.A.
6.6
N.A.
0
20
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
20
80
46.6
53.3
N.A.
6.6
N.A.
13.3
20
Percent
Protein Identity:
36.3
N.A.
N.A.
38.6
33.5
36.6
Protein Similarity:
50.2
N.A.
N.A.
53
48.2
48.8
P-Site Identity:
20
N.A.
N.A.
20
6.6
6.6
P-Site Similarity:
26.6
N.A.
N.A.
26.6
20
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
53
12
65
18
12
24
12
12
18
12
6
12
12
6
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
53
0
0
6
0
0
0
6
30
6
0
0
% D
% Glu:
6
0
0
6
0
6
18
6
42
12
6
6
6
0
0
% E
% Phe:
0
53
0
0
0
0
0
0
0
0
6
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
6
6
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
6
0
% I
% Lys:
12
0
0
0
0
12
6
12
12
6
6
0
6
48
6
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
36
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
6
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% N
% Pro:
6
24
12
12
36
12
48
12
18
12
6
12
12
24
77
% P
% Gln:
6
0
0
0
0
6
0
0
0
0
0
0
6
6
0
% Q
% Arg:
0
0
0
0
0
36
0
0
0
0
6
0
0
0
0
% R
% Ser:
18
0
12
0
0
0
12
6
0
6
6
18
12
6
6
% S
% Thr:
0
6
12
6
0
0
0
48
6
0
42
0
0
6
0
% T
% Val:
0
6
0
6
0
6
0
0
0
48
6
24
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
53
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _